Ceftriaxone

Ceftriaxone2

Ceftriaxone 1,0 g USP

Powder for injection (I.M. / I.V.)

Vials № 50

Each vial contains:

Ceftriaxone  Sodium  USP – 1,0 g.

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Ceftriaxone (1,0 g / 3,5 ml)

Ceftriaxone sodium (I.M.)

1 vial (1,0 g Ceftriaxone) + 1 solvent ampoule (3,5 ml 1% Lidocaine hydrochloride)

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Ceftriaxone (0,5 g / 2,0 ml)

Ceftriaxone sodium (I.M.)

1 vial (0,5 g Ceftriaxone) + 1 solvent ampoule (2,0 ml 1% Lidocaine hydrochloride)

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Ceftriaxone (0,25 g / 2,0 ml)

Ceftriaxone sodium (I.M.)

1 vial (0,25 g Ceftriaxone) + 1 solvent ampoule (2,0 ml 1% Lidocaine hydrochloride)

Ceftriaxone is a third-generation cephalosporin antibiotic.

Like other third-generation cephalosporins, it has broad-spectrum activity against Gram-positive and Gram-negative bacteria.

In most cases, it is considered to be equivalent to cefotaxime in terms of safety and efficacy.

The syn-configuration of the methoxyimino moiety confers resistance to β-lactamase enzymes produced by many Gram-negative bacteria.

The stability of this configuration results in increased activity of ceftriaxone against otherwise-resistant Gram-negative bacteria.

In place of the easily hydrolysed acetyl group of cefotaxime, ceftriaxone has a metabolically stable thiotriazinedione moiety.