Vitamin B1

Vitamin B1. Vitamin B1..jpg2

Thiamine Hydrochloride

Solution for  I.M. injection

Ampoules № 10

Each ampoule contains:

Thiamine Hydrochloride 5% – 50,0 mg / 1,0 ml

Thiamine or  vitamin B1, named as the “thio-vitamine” (“sulfur-containing vitamin”) is a water-soluble vitamin of the B complex.

First named “aneurin” for the detrimental neurological effects if not present in the diet, it was eventually assigned the generic descriptor name vitamin B1. Its phosphate derivatives are involved in many cellular processes. The best-characterized form is thiamine pyrophosphate (TPP), a coenzyme in the catabolism of sugars and amino acids.

Thiamine is used in the biosynthesis of the neurotransmitter acetylcholine and gamma – aminobutyric acid (GABA).

Thiamine hydrochloride injection is used to treat or prevent vitamin B1 deficiency.

Thiamine hydrochloride injection is used to treat beriberi, a serious condition caused by prolonged lack of vitamin B1 (Wernicke’s encephalopathy syndrome and e.t.c.).

Thiamine hydrochloride has been used in thiamine-responsive maple syrup urine disease and subacute necrotizing encephalomyelopathy (Leigh’s disease).